A technetium intermediate specifically promotes deprotection of trifluoroacetyl HYNIC during radiolabelling under mild conditions.
نویسندگان
چکیده
The trifluoroacetyl group protects the nucleophilic HYNIC from unwanted side reactions yet allows radiolabelling with technetium-99m under mild conditions, due to efficient and specific promotion of deprotection by a technetium complex intermediate.
منابع مشابه
Mild deprotection of methylene acetals in combination with trimethylsilyl triflate-2,2'-bipyridyl.
The facile deprotection of methylene acetal protection of diols under mild conditions is established. The combination of trimethylsilyl triflate (TMSOTf) and 2,2'-bipyridyl followed by a weakly acidic hydrolysis was effective and the substrates having acid sensitive functional groups can be tolerated under the stated conditions. The selective deprotection between methylene acetal and benzopheno...
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ورودعنوان ژورنال:
- Dalton transactions
دوره 22 شماره
صفحات -
تاریخ انتشار 2008